Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

10.1021/acsmedchemlett.0c00588

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Bibliographic Details
Main Authors:	Tan, Yu Jia, Li, Ming, Gunawan, Gregory Adrian, Nyantakyi, Samuel Agyei, Dick, Thomas, Go, Mei-Lin, Lam, Yulin
Other Authors:	CHEMISTRY
Format:	Article
Language:	English
Published:	AMER CHEMICAL SOC 2023
Subjects:	Science & Technology Life Sciences & Biomedicine Chemistry, Medicinal Pharmacology & Pharmacy Mycobactericidal activity indolylmethylamines MmpL3 water solubility BIOLOGICAL EVALUATION MMPL3 INHIBITION
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/243003
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Institution:	National University of Singapore
Language:	English

Description
Summary:	10.1021/acsmedchemlett.0c00588