Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial

• Main Authors: Natasha Howard, Ishola, D, Manno, D, Afolabi, MO, Keshinro, B, Bockstal, V, Rogers, B, Owusu-Kyei, K, Serry-Bangura, A, Swaray, I, Lowe, B, Kowuor, D, Baiden, F, Mooney, T, Smout, E, Köhn, B, Otieno, GT, Jusu, M, Foster, J, Samai, M, Deen, GF, Larson, H, Lees, S, Goldstein, N, Gallagher, KE, Gaddah, A, Heerwegh, D, Callendret, B, Luhn, K, Robinson, C, Leyssen, M, Greenwood, B, Douoguih, M, Leigh, B, Watson-Jones, D, Kargbo, M, Bockarie, E, James, NL, Kabbah, A, Kamara, A, Koroma, KH, Langley, SO, William, N, Kessebeh, R, Conteh, L, Allieu, K, Bangura, K, Bangura, MS, Bangura, MA, Jalloh, H, Jalloh, AB, Kamara, I, Kamara, M, Konteh, A, Koroma, S, Marrah, C, Sesay, M, Sesay, MT, Deen, AT, Jalloh, A, Kaimbay, RM, Kain, D, Kamara, EL, Kamara, MP, Kamara, OJ, Kamara, SLM, Kanneh, M, Koroma, AH, Lahai, D, Mansaray, IS, Marah, WS, Massaquoi, MJ, Nabie, A, Saidu, NS, Samai, I, Tengheh, JN, Turay, AS, Fornah, A, Sesay, F, Sow, A, Swaray, E, Mansaray, F, Ade-Cole, T, Bangura, LM, Conteh, ML, Koroma, AM, Koroma, M, Sam, A, Scott, T, Sessie, T, Sunders, JHC, Turay, SIS, Weekes, J, Sheku, M, Gibson, L, Ahamed, I, Allieu, W, Kabba, DU
• Other Authors: DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
• Format: Article
• Published: Elsevier BV 2023
• Subjects: Adult; Antibodies, Viral; Democratic Republic of the Congo; Double-Blind Method; Ebola Vaccines; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Humans; Immunity, Humoral; Immunogenicity, Vaccine; Male; Sierra Leone; Vaccination; Vaccines, DNA; Viral Envelope Proteins; Viral Vaccines
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/243189
• Institution: National University of Singapore

10.1016/S1473-3099(21)00125-0