SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition

10.1038/s41698-023-00486-6

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Main Authors: Lai, Xianning, Lui, Sarah Kit Leng, Lam, Hiu Yan, Adachi, Yuta, Sim, Wen Jing, Vasilevski, Natali, Armstrong, Nicola J, Bridgeman, Stephanie Claire, Main, Nathan Michael, Tan, Tuan Zea, Tirnitz-Parker, Janina EE, Thiery, Jean Paul, Ebi, Hiromichi, Kumar, Alan Prem, Eichhorn, Pieter Johan Adam
Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
Format: Article
Language:English
Published: NATURE PORTFOLIO 2024
Subjects:
EMT
Online Access:https://scholarbank.nus.edu.sg/handle/10635/248467
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Institution: National University of Singapore
Language: English
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spelling sg-nus-scholar.10635-2484672024-05-20T01:31:23Z SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition Lai, Xianning Lui, Sarah Kit Leng Lam, Hiu Yan Adachi, Yuta Sim, Wen Jing Vasilevski, Natali Armstrong, Nicola J Bridgeman, Stephanie Claire Main, Nathan Michael Tan, Tuan Zea Tirnitz-Parker, Janina EE Thiery, Jean Paul Ebi, Hiromichi Kumar, Alan Prem Eichhorn, Pieter Johan Adam CANCER SCIENCE INSTITUTE OF SINGAPORE BIOMED INST FOR GLOBAL HEALTH RES & TECH BIOCHEMISTRY Science & Technology Life Sciences & Biomedicine Oncology UBIQUITIN LIGASE RECEPTOR RESISTANCE SMAD7 TARGETS EMT 10.1038/s41698-023-00486-6 NPJ PRECISION ONCOLOGY 7 1 2024-05-20T00:45:41Z 2024-05-20T00:45:41Z 2023-12-15 2024-05-18T02:22:08Z Article Lai, Xianning, Lui, Sarah Kit Leng, Lam, Hiu Yan, Adachi, Yuta, Sim, Wen Jing, Vasilevski, Natali, Armstrong, Nicola J, Bridgeman, Stephanie Claire, Main, Nathan Michael, Tan, Tuan Zea, Tirnitz-Parker, Janina EE, Thiery, Jean Paul, Ebi, Hiromichi, Kumar, Alan Prem, Eichhorn, Pieter Johan Adam (2023-12-15). SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition. NPJ PRECISION ONCOLOGY 7 (1). ScholarBank@NUS Repository. https://doi.org/10.1038/s41698-023-00486-6 2397-768X https://scholarbank.nus.edu.sg/handle/10635/248467 en NATURE PORTFOLIO Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Oncology
UBIQUITIN LIGASE
RECEPTOR
RESISTANCE
SMAD7
TARGETS
EMT
spellingShingle Science & Technology
Life Sciences & Biomedicine
Oncology
UBIQUITIN LIGASE
RECEPTOR
RESISTANCE
SMAD7
TARGETS
EMT
Lai, Xianning
Lui, Sarah Kit Leng
Lam, Hiu Yan
Adachi, Yuta
Sim, Wen Jing
Vasilevski, Natali
Armstrong, Nicola J
Bridgeman, Stephanie Claire
Main, Nathan Michael
Tan, Tuan Zea
Tirnitz-Parker, Janina EE
Thiery, Jean Paul
Ebi, Hiromichi
Kumar, Alan Prem
Eichhorn, Pieter Johan Adam
SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
description 10.1038/s41698-023-00486-6
author2 CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet CANCER SCIENCE INSTITUTE OF SINGAPORE
Lai, Xianning
Lui, Sarah Kit Leng
Lam, Hiu Yan
Adachi, Yuta
Sim, Wen Jing
Vasilevski, Natali
Armstrong, Nicola J
Bridgeman, Stephanie Claire
Main, Nathan Michael
Tan, Tuan Zea
Tirnitz-Parker, Janina EE
Thiery, Jean Paul
Ebi, Hiromichi
Kumar, Alan Prem
Eichhorn, Pieter Johan Adam
format Article
author Lai, Xianning
Lui, Sarah Kit Leng
Lam, Hiu Yan
Adachi, Yuta
Sim, Wen Jing
Vasilevski, Natali
Armstrong, Nicola J
Bridgeman, Stephanie Claire
Main, Nathan Michael
Tan, Tuan Zea
Tirnitz-Parker, Janina EE
Thiery, Jean Paul
Ebi, Hiromichi
Kumar, Alan Prem
Eichhorn, Pieter Johan Adam
author_sort Lai, Xianning
title SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
title_short SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
title_full SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
title_fullStr SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
title_full_unstemmed SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition
title_sort shp2 inhibitors maintain tgfβ signalling through smurf2 inhibition
publisher NATURE PORTFOLIO
publishDate 2024
url https://scholarbank.nus.edu.sg/handle/10635/248467
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