MICROARRAY-ASSISTED DISCOVERY OF PROTEIN-PROTEIN INTERACTION INHIBITORS AND ENZYME PROBES

MICROARRAY-ASSISTED DISCOVERY OF PROTEIN-PROTEIN INTERACTION INHIBITORS AND ENZYME PROBES

Ph.D

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	NA ZHENKUN
مؤلفون آخرون:	CHEMISTRY
التنسيق:	Theses and Dissertations
اللغة:	English
منشور في:	2014
الموضوعات:	Microarray, High-throughput, screening tools, protein-protein interaction, Inhibitor, probe,
الوصول للمادة أونلاين:	http://scholarbank.nus.edu.sg/handle/10635/53621
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

High-throughput methodologies for enzyme inhibitor profiling
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Intein-mediated biotinylation of proteins and its application in protein microarray
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BEYOND PARP: CHEMICAL BIOLOGY STUDY OF PARP SUBFAMILY AND OPTIMIZATION OF MICROARRAY
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An in silico approach for the discovery of CDK5/p25 interaction inhibitors
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DESIGN AND SYNTHESIS OF CHEMICAL PROBES FOR IMAGING AND INHIBITOR SCREENING OF TARGETED PROTEINS
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Nanostructured dendrimer modified glass surfaces for protein microarray
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DEVELOPING HIGH-THROUGHPUT APPROACHES FOR ENZYME SCREENING AND PROTEOMIC PROFILING
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Recent developments in microarray-based enzyme assays: From functional annotation to substrate/inhibitor fingerprinting
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Developing High-Throughput Chemical Approaches For Proteomic Profiling Of Aspartic Proteases And Protein Kinases
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Chemical biology of matrix metalloproteases
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Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors
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A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53
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Developing chemical biology approaches for the activity-based investigations of reversible protein phosphorylation-mediating enzymes
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Development of protein microarrays and label-free microfluidic immunoassays
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High-throughput screening of metalloproteases using small molecule microarrays
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First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors
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Intein-mediated generation of N-terminal cysteine proteins and their applications in live cell bioimaging and protein microarray
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DNA-directed assembly of protein microarrays
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Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates
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Triazaspiroalkenes as potential inhibitors of dihydrofolate reductase
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In Silico Methodologies for Selection and Prioritization of Compounds in Drug Discovery
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Prediction of ligand-binding proteins and their inhibitors: machine learning approach
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Targeting the bacterial epitranscriptome for antibiotic development : discovery of novel tRNA-(N1G37) methyltransferase (TrmD) inhibitors
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Function of the SIRTI protein deacetylase in cancer
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Spatially addressable protein array: ssDNA-directed assembly for antibody microarray
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On-line chromatographic screening of matrix metalloproteinase inhibitors using immobilized MMP-9 enzyme reactor
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Probing protein dynamics and protein-protein interaction by NMR spectroscopy
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Virtual screening of selective multitarget kinase inhibitors by combinatorial support vector machines
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Microfluidics and microarray based approaches to biological analysis
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