Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation

• Main Authors: Parker, L.J., Italiano, L.C., Morton, C.J., Hancock, N.C., Ascher, D.B., Aitken, J.B., Harris, H.H., Campomanes, P., Rothlisberger, U., De Luca, A., Lo Bello, M., Ang, W.H., Dyson, P.J., Parker, M.W.
• Other Authors: CHEMISTRY
• Format: Article
• Published: 2014
• Subjects: antitumor agents; detoxification; ethacrynic acid; glutathione transferases; X-ray crystallography
• Online Access: http://scholarbank.nus.edu.sg/handle/10635/94928
• Institution: National University of Singapore

10.1002/chem.201100586