Neurotrophin-4/5 Treatment Reduces Infarct Size in Rats with Middle Cerebral Artery Occlusion

• Main Authors: CHAN, Kay Min, LAM, Diem-Thuy N., PONG, Kevin, WIDMER, Hans R., HEFTI, Franz
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 1996
• Subjects: Neurotrophin trk receptor infarct stroke; Medicine and Health Sciences
• Online Access: https://ink.library.smu.edu.sg/lkcsb_research/4914
• Institution: Singapore Management University

The aim of this study was to determine whether neurotrophin-4/5 (NT-4/5) treatment alters infarction volume following permanent focal cerebral ischemia in the rat. Permanent focal cerebral ischemia was produced in adult male rats by intraluminal occlusion of the right middle cerebral artery. NT-4/5...