Prediction of Protein Subcellular Localization: A Machine Learning Approach
Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protei...
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sg-smu-ink.sis_research-25252018-08-16T06:45:05Z Prediction of Protein Subcellular Localization: A Machine Learning Approach SHIM, Kyong Jin Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protein subcellular localization that use resources concerning Gene Ontology and secondary structures. Using the spectrum kernel for feature representation of amino acid sequences and secondary structures, we explore an SVM-based learning method that classifies six subcellular localization sites: endoplasmic reticulum, extracellular, Golgi, membrane, mitochondria, and nucleus. 2010-06-01T07:00:00Z text application/pdf https://ink.library.smu.edu.sg/sis_research/1526 https://ink.library.smu.edu.sg/context/sis_research/article/2525/viewcontent/10_014.pdf http://creativecommons.org/licenses/by-nc-nd/4.0/ Research Collection School Of Computing and Information Systems eng Institutional Knowledge at Singapore Management University Databases and Information Systems Numerical Analysis and Scientific Computing |
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Databases and Information Systems Numerical Analysis and Scientific Computing SHIM, Kyong Jin Prediction of Protein Subcellular Localization: A Machine Learning Approach |
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Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protein subcellular localization that use resources concerning Gene Ontology and secondary structures. Using the spectrum kernel for feature representation of amino acid sequences and secondary structures, we explore an SVM-based learning method that classifies six subcellular localization sites: endoplasmic reticulum, extracellular, Golgi, membrane, mitochondria, and nucleus. |
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SHIM, Kyong Jin |
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SHIM, Kyong Jin |
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SHIM, Kyong Jin |
title |
Prediction of Protein Subcellular Localization: A Machine Learning Approach |
title_short |
Prediction of Protein Subcellular Localization: A Machine Learning Approach |
title_full |
Prediction of Protein Subcellular Localization: A Machine Learning Approach |
title_fullStr |
Prediction of Protein Subcellular Localization: A Machine Learning Approach |
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Prediction of Protein Subcellular Localization: A Machine Learning Approach |
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prediction of protein subcellular localization: a machine learning approach |
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Institutional Knowledge at Singapore Management University |
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2010 |
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https://ink.library.smu.edu.sg/sis_research/1526 https://ink.library.smu.edu.sg/context/sis_research/article/2525/viewcontent/10_014.pdf |
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