Prediction of Protein Subcellular Localization: A Machine Learning Approach

Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protei...

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Main Author: SHIM, Kyong Jin
Format: text
Language:English
Published: Institutional Knowledge at Singapore Management University 2010
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Online Access:https://ink.library.smu.edu.sg/sis_research/1526
https://ink.library.smu.edu.sg/context/sis_research/article/2525/viewcontent/10_014.pdf
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spelling sg-smu-ink.sis_research-25252018-08-16T06:45:05Z Prediction of Protein Subcellular Localization: A Machine Learning Approach SHIM, Kyong Jin Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protein subcellular localization that use resources concerning Gene Ontology and secondary structures. Using the spectrum kernel for feature representation of amino acid sequences and secondary structures, we explore an SVM-based learning method that classifies six subcellular localization sites: endoplasmic reticulum, extracellular, Golgi, membrane, mitochondria, and nucleus. 2010-06-01T07:00:00Z text application/pdf https://ink.library.smu.edu.sg/sis_research/1526 https://ink.library.smu.edu.sg/context/sis_research/article/2525/viewcontent/10_014.pdf http://creativecommons.org/licenses/by-nc-nd/4.0/ Research Collection School Of Computing and Information Systems eng Institutional Knowledge at Singapore Management University Databases and Information Systems Numerical Analysis and Scientific Computing
institution Singapore Management University
building SMU Libraries
continent Asia
country Singapore
Singapore
content_provider SMU Libraries
collection InK@SMU
language English
topic Databases and Information Systems
Numerical Analysis and Scientific Computing
spellingShingle Databases and Information Systems
Numerical Analysis and Scientific Computing
SHIM, Kyong Jin
Prediction of Protein Subcellular Localization: A Machine Learning Approach
description Subcellular localization is a key functional characteristic of proteins. Optimally combining available information is one of the key challenges in today's knowledge-based subcellular localization prediction approaches. This study explores machine learning approaches for the prediction of protein subcellular localization that use resources concerning Gene Ontology and secondary structures. Using the spectrum kernel for feature representation of amino acid sequences and secondary structures, we explore an SVM-based learning method that classifies six subcellular localization sites: endoplasmic reticulum, extracellular, Golgi, membrane, mitochondria, and nucleus.
format text
author SHIM, Kyong Jin
author_facet SHIM, Kyong Jin
author_sort SHIM, Kyong Jin
title Prediction of Protein Subcellular Localization: A Machine Learning Approach
title_short Prediction of Protein Subcellular Localization: A Machine Learning Approach
title_full Prediction of Protein Subcellular Localization: A Machine Learning Approach
title_fullStr Prediction of Protein Subcellular Localization: A Machine Learning Approach
title_full_unstemmed Prediction of Protein Subcellular Localization: A Machine Learning Approach
title_sort prediction of protein subcellular localization: a machine learning approach
publisher Institutional Knowledge at Singapore Management University
publishDate 2010
url https://ink.library.smu.edu.sg/sis_research/1526
https://ink.library.smu.edu.sg/context/sis_research/article/2525/viewcontent/10_014.pdf
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