Towards Inferring Protein Interactions: Challenges and Solutions

• Main Authors: ZHANG, Ya, ZHA, Hongyuan, CHU, Chao-Hsien, JI, Xiang, CHEN, X. W.
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2006
• Subjects: Bioinformatics; Computer Sciences
• Online Access: https://ink.library.smu.edu.sg/sis_research/1790; http://asp.eurasipjournals.com/content/2006/1/037349/abstract
• Institution: Singapore Management University

Discovering interacting proteins has been an essential part of functional genomics. However, existing experimental techniques only uncover a small portion of any interactome. Furthermore, these data often have a very high false rate. By conceptualizing the interactions at domain level, we provide a...