Beta Atomic Contacts: Identifying Critical Specific Contacts in Protein Binding Interfaces

• Main Authors: LU, Qian, KWOH, Chee Keong, HOI, Steven C. H.
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2013
• Subjects: Crystallography; X-Ray; Decision Trees; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Chemical Models; Molecular Models; Protein Interaction Domains and Motifs; Quaternary Protein Structure; Proteins; Support Vector Machines; Bioinformatics; Computer Sciences; Databases and Information Systems
• Online Access: https://ink.library.smu.edu.sg/sis_research/2296; https://ink.library.smu.edu.sg/context/sis_research/article/3296/viewcontent/journal.pone.0059737.PDF
• Institution: Singapore Management University

Specific binding between proteins plays a crucial role in molecular functions and biological processes. Protein binding interfaces and their atomic contacts are typically defined by simple criteria, such as distance-based definitions that only use some threshold of spatial distance in previous studi...