PGMC: a framework for probabilistic graphic model combination

PGMC: a framework for probabilistic graphic model combination

Decision making in biomedicine often involves incorporating new evidences into existing or working models reflecting the decision problems at hand. We propose a new framework that facilitates effective and incremental integration of multiple probabilistic graphical models. The proposed framework aim...

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Bibliographic Details
Main Authors: Jiang, Chang-an, Tze-Yun LEONG, Poh, Kim-Leng
Format: text
Language:English
Published: Institutional Knowledge at Singapore Management University 2005
Subjects:
Algorithm; article
Artificial neural network
Bayes theorem
Decision support system
Feasibility study
Heart disease
Human
Statistical model
Computer Sciences
Health Information Technology
Online Access:https://ink.library.smu.edu.sg/sis_research/3034
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Institution: Singapore Management University
Language: English
Description
Summary:Decision making in biomedicine often involves incorporating new evidences into existing or working models reflecting the decision problems at hand. We propose a new framework that facilitates effective and incremental integration of multiple probabilistic graphical models. The proposed framework aims to minimize time and effort required to customize and extend the original models through preserving the conditional independence relationships inherent in two types of probabilistic graphical models: Bayesian networks and influence diagrams. We present a four-step algorithm to systematically combine the qualitative and the quantitative parts of the different models; we also describe three heuristic methods for target variable generation to reduce the complexity of the integrated models. Preliminary results from a case study in heart disease diagnosis demonstrate the feasibility and potential for applying the proposed framework in real applications.

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