Identifying essential pairwise interactions in elastic network model using the alpha shape theory

• Main Authors: XIA, Fei, TONG, Dudu, YANG, Lifeng, WANG, Dayong, HOI, Steven C. H., KOEHL, Patrice, LU, Lanyuan
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2014
• Subjects: ANM; elastic network model; alpha shape theory; ENM; Databases and Information Systems
• Online Access: https://ink.library.smu.edu.sg/sis_research/4038
• Institution: Singapore Management University

Elastic network models (ENM) are based on the idea that the geometry of a protein structure provides enough information for computing its fluctuations around its equilibrium conformation. This geometry is represented as an elastic network (EN) that is, a network of links between residues. A spring i...