Proteome database of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC or hepatoma) is the most common primary cancer of the liver. Persistent viral infection by the hepatic B or C virus is probably the most important cause of HCC worldwide. It is responsible for approximately one million deaths each year, predominantly in the underdevelop...
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sg-smu-ink.sis_research-58802020-02-13T08:47:03Z Proteome database of hepatocellular carcinoma. LIANG, Cynthia NEO, Jason LO, Siaw Ling TAN, Gek San SEOW, Teck Keong CHUNG, Maxey Hepatocellular carcinoma (HCC or hepatoma) is the most common primary cancer of the liver. Persistent viral infection by the hepatic B or C virus is probably the most important cause of HCC worldwide. It is responsible for approximately one million deaths each year, predominantly in the underdeveloped and developing countries, but its incidence is also on the rise in the developed countries. For most patients suffering from HCC, long-term survival is rare, as they are presented late and are often unsuitable for curative treatment. Thus there is great interest to identify novel HCC diagnostic markers for early detection of the disease, and tumour specific associated proteins as potential therapeutic targets in the treatment of HCC. Proteome analyses of HCC cell lines and liver tumour tissues should facilitate the screening and discovery of these HCC proteins. The creation of a comprehensive HCC proteome database would be an important first step towards achieving this goal. This review presents an update of the two-dimensional electrophoresis proteome database of the cell line, HCC-M, which is also now freely accessible through the World Wide Web at http://proteome.btc.nus.edu.sg/hccm/. 2002-05-01T07:00:00Z text application/pdf https://ink.library.smu.edu.sg/sis_research/4877 info:doi/10.1016/s1570-0232(02)00041-7 https://ink.library.smu.edu.sg/context/sis_research/article/5880/viewcontent/Proteome___PV.pdf http://creativecommons.org/licenses/by-nc-nd/4.0/ Research Collection School Of Computing and Information Systems eng Institutional Knowledge at Singapore Management University Reviews Proteomics Hepatocellular carcinoma Computer Engineering Databases and Information Systems |
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Reviews Proteomics Hepatocellular carcinoma Computer Engineering Databases and Information Systems LIANG, Cynthia NEO, Jason LO, Siaw Ling TAN, Gek San SEOW, Teck Keong CHUNG, Maxey Proteome database of hepatocellular carcinoma. |
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Hepatocellular carcinoma (HCC or hepatoma) is the most common primary cancer of the liver. Persistent viral infection by the hepatic B or C virus is probably the most important cause of HCC worldwide. It is responsible for approximately one million deaths each year, predominantly in the underdeveloped and developing countries, but its incidence is also on the rise in the developed countries. For most patients suffering from HCC, long-term survival is rare, as they are presented late and are often unsuitable for curative treatment. Thus there is great interest to identify novel HCC diagnostic markers for early detection of the disease, and tumour specific associated proteins as potential therapeutic targets in the treatment of HCC. Proteome analyses of HCC cell lines and liver tumour tissues should facilitate the screening and discovery of these HCC proteins. The creation of a comprehensive HCC proteome database would be an important first step towards achieving this goal. This review presents an update of the two-dimensional electrophoresis proteome database of the cell line, HCC-M, which is also now freely accessible through the World Wide Web at http://proteome.btc.nus.edu.sg/hccm/. |
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text |
author |
LIANG, Cynthia NEO, Jason LO, Siaw Ling TAN, Gek San SEOW, Teck Keong CHUNG, Maxey |
author_facet |
LIANG, Cynthia NEO, Jason LO, Siaw Ling TAN, Gek San SEOW, Teck Keong CHUNG, Maxey |
author_sort |
LIANG, Cynthia |
title |
Proteome database of hepatocellular carcinoma. |
title_short |
Proteome database of hepatocellular carcinoma. |
title_full |
Proteome database of hepatocellular carcinoma. |
title_fullStr |
Proteome database of hepatocellular carcinoma. |
title_full_unstemmed |
Proteome database of hepatocellular carcinoma. |
title_sort |
proteome database of hepatocellular carcinoma. |
publisher |
Institutional Knowledge at Singapore Management University |
publishDate |
2002 |
url |
https://ink.library.smu.edu.sg/sis_research/4877 https://ink.library.smu.edu.sg/context/sis_research/article/5880/viewcontent/Proteome___PV.pdf |
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