Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumors

• Main Authors: HOOS, Axel, Urist, M. J., Stojadinovic, A., Mastorides, S., Dudas, M., LEUNG, Denis H. Y.
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2001
• Subjects: Econometrics; Medicine and Health Sciences
• Online Access: https://ink.library.smu.edu.sg/soe_research/9; https://ink.library.smu.edu.sg/context/soe_research/article/1008/viewcontent/2581.pdf
• Institution: Singapore Management University

Tissue microarrays allow high-throughput molecular profiling of cancer specimens by immunohistochemistry. Phenotype information of sections from arrayed biopsies on a multitissue block needs to be representative of full sections, as protein expression varies throughout the entire tumor specimen. To...