Multiple Testing to Establish Superiority/Equivalence of a New Treatment Compared with K Standard Treatments for Unbalanced Designs

• Main Authors: KWONG, Koon Shing, CHEUNG, Siu Hung, CHAN, Wai-Sum
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2004
• Subjects: Coherence property; Equivalent efficacy; Familywise error rate; Multivariate t-distribution; Econometrics; Medicine and Health Sciences
• Online Access: https://ink.library.smu.edu.sg/soe_research/35; https://ink.library.smu.edu.sg/context/soe_research/article/1034/viewcontent/Kwong_et_al_2004_MultipleTesting.pdf
• Institution: Singapore Management University

In clinical studies, multiple superiority/equivalence testing procedures can be applied to classify a new treatment as superior, equivalent (same therapeutic effect), or inferior to each set of standard treatments. Previous stepwise approaches (Dunnett and Tamhane, 1997, Statistics in Medicine 16, 2...