Surgical Management of Intra-Abdominal Desmoid Tumors

Intra-abdominal desmoids are uncommon neoplasms. The aggressive nature of these tumours and the potential for major morbidity secondary to resection can present a difficult surgical dilemma.Patients with histologically confirmed intra-abdominal desmoid tumours undergoing laparotomy were identified f...

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Main Authors: Smith, A. J., Lewis, J. J., Merchant, N. B., Leung, Denis H. Y., Woodruff, J. M., Brennan, M. F.
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Language:English
Published: Institutional Knowledge at Singapore Management University 2000
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Online Access:https://ink.library.smu.edu.sg/soe_research/38
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spelling sg-smu-ink.soe_research-10372010-09-23T05:48:03Z Surgical Management of Intra-Abdominal Desmoid Tumors Smith, A. J. Lewis, J. J. Merchant, N. B. Leung, Denis H. Y. Woodruff, J. M. Brennan, M. F. Intra-abdominal desmoids are uncommon neoplasms. The aggressive nature of these tumours and the potential for major morbidity secondary to resection can present a difficult surgical dilemma.Patients with histologically confirmed intra-abdominal desmoid tumours undergoing laparotomy were identified from a prospective database. Clinical features and outcomes in this group were evaluated.The study group comprised 24 patients. Sixteen patients underwent complete resection of the tumour while eight had biopsy only, with or without intestinal bypass. Small intestinal resection was performed in 12 patients, including three who had a near-total enterectomy. Median follow-up was 62 months, with an actuarial overall survival rate of 73 per cent at 10 years. There was no difference in survival rate between completely resected and unresected patients (P = 0·73). There were seven deaths in the entire group, of which four were in those undergoing complete resection.Operation can cure patients with intra-abdominal desmoid tumours, but may result in significant morbidity, especially from loss of small intestine. No other therapy is a predictably good alternative to operation but the natural history of desmoids is often characterized by prolonged periods of stability or even regression. A period of watchful waiting, until significant symptoms develop, may be the most appropriate course in patients who risk mesenteric vascular injury or substantial enterectomy with attempts at resection. © 2000 British Journal of Surgery Society Ltd 2000-01-01T08:00:00Z text https://ink.library.smu.edu.sg/soe_research/38 info:doi/10.1046/j.1365-2168.2000.01400.x Research Collection School Of Economics eng Institutional Knowledge at Singapore Management University Econometrics Medicine and Health Sciences
institution Singapore Management University
building SMU Libraries
continent Asia
country Singapore
Singapore
content_provider SMU Libraries
collection InK@SMU
language English
topic Econometrics
Medicine and Health Sciences
spellingShingle Econometrics
Medicine and Health Sciences
Smith, A. J.
Lewis, J. J.
Merchant, N. B.
Leung, Denis H. Y.
Woodruff, J. M.
Brennan, M. F.
Surgical Management of Intra-Abdominal Desmoid Tumors
description Intra-abdominal desmoids are uncommon neoplasms. The aggressive nature of these tumours and the potential for major morbidity secondary to resection can present a difficult surgical dilemma.Patients with histologically confirmed intra-abdominal desmoid tumours undergoing laparotomy were identified from a prospective database. Clinical features and outcomes in this group were evaluated.The study group comprised 24 patients. Sixteen patients underwent complete resection of the tumour while eight had biopsy only, with or without intestinal bypass. Small intestinal resection was performed in 12 patients, including three who had a near-total enterectomy. Median follow-up was 62 months, with an actuarial overall survival rate of 73 per cent at 10 years. There was no difference in survival rate between completely resected and unresected patients (P = 0·73). There were seven deaths in the entire group, of which four were in those undergoing complete resection.Operation can cure patients with intra-abdominal desmoid tumours, but may result in significant morbidity, especially from loss of small intestine. No other therapy is a predictably good alternative to operation but the natural history of desmoids is often characterized by prolonged periods of stability or even regression. A period of watchful waiting, until significant symptoms develop, may be the most appropriate course in patients who risk mesenteric vascular injury or substantial enterectomy with attempts at resection. © 2000 British Journal of Surgery Society Ltd
format text
author Smith, A. J.
Lewis, J. J.
Merchant, N. B.
Leung, Denis H. Y.
Woodruff, J. M.
Brennan, M. F.
author_facet Smith, A. J.
Lewis, J. J.
Merchant, N. B.
Leung, Denis H. Y.
Woodruff, J. M.
Brennan, M. F.
author_sort Smith, A. J.
title Surgical Management of Intra-Abdominal Desmoid Tumors
title_short Surgical Management of Intra-Abdominal Desmoid Tumors
title_full Surgical Management of Intra-Abdominal Desmoid Tumors
title_fullStr Surgical Management of Intra-Abdominal Desmoid Tumors
title_full_unstemmed Surgical Management of Intra-Abdominal Desmoid Tumors
title_sort surgical management of intra-abdominal desmoid tumors
publisher Institutional Knowledge at Singapore Management University
publishDate 2000
url https://ink.library.smu.edu.sg/soe_research/38
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