Conditional Probability of Significance for Early Stopping in Favor of H0

Early stopping is often desirable in a large clinical trial if data accumulated during the trial has little evidence to support the alternative hypothesis or the null result seems inevitable. This motivates, for example, the conditional power and predictive power approaches for early stopping in fav...

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Bibliographic Details
Main Authors: Wang, Y. G., Leung, Denis H. Y.
Format: text
Language:English
Published: Institutional Knowledge at Singapore Management University 2002
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Online Access:https://ink.library.smu.edu.sg/soe_research/364
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Institution: Singapore Management University
Language: English