Sample Size, Error Rates and Optimality Considerations for Phase II Clinical Trials

• المؤلفون الرئيسيون: Wang, Y. G., Leung, Denis H. Y., Li, M., TAN, S. B.
• التنسيق: text
• اللغة: English
• منشور في: Institutional Knowledge at Singapore Management University 2005
• الموضوعات: Applied Statistics; Economics
• الوصول للمادة أونلاين: https://ink.library.smu.edu.sg/soe_research/418

So far, most Phase II trials have been designed and analysed under a frequentist framework. Under this framework, a trial is designed so that the overall Type I and Type II errors of the trial are controlled at some desired levels. Recently, a number of articles have advocated the use of Bayesian de...