Evaluation of Dose-Intense Ifosfamide, with and without Edatrexate, in Adults with Sarcoma

• Main Authors: Casper, E. S., Schwartz, G. M., Leung, Denis H. Y., Sugarman, A., Bertino, J.
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 1999
• Subjects: Economics
• Online Access: https://ink.library.smu.edu.sg/soe_research/494
• Institution: Singapore Management University

Purpose. To define the maximally tolerated dose (MTD) of ifosfamide when given with G-CSF on an every other week schedule, and to define the MTD of edatrexate that can be given every two weeks with an intense schedule of ifosfamide. Patients and Methods. Forty-one patients with metastatic or unresec...