Sample size determination in step-up testing procedures for multiple comparisons with a control

• Main Authors: KWONG, Koon Shing, CHUENG, Siu Hung, WEN, Miin‐Jye
• 格式: text
• 語言: English
• 出版: Institutional Knowledge at Singapore Management University 2010
• 主題: multiple comparisons with a control; power function; step-up test; familywise error rate; Econometrics; Health Economics
• 在線閱讀: https://ink.library.smu.edu.sg/soe_research/1272; https://doi.org/10.1002/sim.4045
• 機構: Singapore Management University

Step-up procedures have been shown to be powerful testing methods in clinical trials for comparisons of several treatments with a control. In this paper, a determination of the optimal sample size for a step-up procedure that allows a pre-specified power level to be attained is discussed. Various de...