Optimal design of p-value consistent step-up procedures for multiple comparisons with a control in direction-mixed families

• Main Authors: KWONG, Koon Shing, CHEUNG, Siu Hung
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2012
• Subjects: Multiple comparisons with a control; Power function; Step-up multiple test; Optimal sample size; Familywise error rate; Econometrics
• Online Access: https://ink.library.smu.edu.sg/soe_research/1412; https://ink.library.smu.edu.sg/context/soe_research/article/2411/viewcontent/OptimalDesign_p_value_2012.pdf
• Institution: Singapore Management University

It is common in clinical studies for several treatments to be compared to a control. Most of the related statistical techniques have been developed to accommodate inferential families in which all hypotheses are either one- or two-sided such that the familywise error rate is controlled at a specifie...