The ethics of placebo-controlled trials in developing countries to prevent mother-to-child transmission of HIV

• Main Author: WILLIAMS, John N.
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2000
• Subjects: Ethical principles; Placebo-trials; women; Thailand; Helsinki Declaration; Medicine and Health Sciences; Philosophy
• Online Access: https://ink.library.smu.edu.sg/soss_research/2; https://ink.library.smu.edu.sg/context/soss_research/article/1001/viewcontent/WilliamsJEthicsPlaceboControlledTrials.pdf
• Institution: Singapore Management University

Placebo-trials on HIV-infected pregnant women in developing countries like Thailand and Uganda have provoked recent controversy. Such experiments aim to find a treatment that will cut the rate of vertical transmission more efficiently than existing treatments like zidovudine. This scenario is first...