Ethnobotany and ethnopharmacology of Tabernaemontana divaricata

Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T....

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Main Authors: Pratchayasakul W., Pongchaidecha A., Chattipakorn N., Chattipakorn S.
Format: Review
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-51349097371&partnerID=40&md5=b9fb957ef51f29ae44d990be182f8c87
http://cmuir.cmu.ac.th/handle/6653943832/1026
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-10262014-08-29T09:17:37Z Ethnobotany and ethnopharmacology of Tabernaemontana divaricata Pratchayasakul W. Pongchaidecha A. Chattipakorn N. Chattipakorn S. Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-alkaloidal constituents. Included, are the characteristics of 66 alkaloids isolated and identified from T. divaricata. Non-alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also documented. Chemotaxonomic aspects of each alkaloid as well as information regarding the pharmacology of crude extracts and individual alkaloids from T. divaricata have been assembled and appraised. The beneficial properties of T. divaricata are antioxidant, anti-infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. The augmentation of cholinergic function may be of therapeutic benefit for many neurodegenerative diseases, particularly myasthenia gravis and Alzheimer's disease. 2014-08-29T09:17:37Z 2014-08-29T09:17:37Z 2008 Review 09715916 18577786 IMIRE http://www.scopus.com/inward/record.url?eid=2-s2.0-51349097371&partnerID=40&md5=b9fb957ef51f29ae44d990be182f8c87 http://cmuir.cmu.ac.th/handle/6653943832/1026 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-alkaloidal constituents. Included, are the characteristics of 66 alkaloids isolated and identified from T. divaricata. Non-alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also documented. Chemotaxonomic aspects of each alkaloid as well as information regarding the pharmacology of crude extracts and individual alkaloids from T. divaricata have been assembled and appraised. The beneficial properties of T. divaricata are antioxidant, anti-infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. The augmentation of cholinergic function may be of therapeutic benefit for many neurodegenerative diseases, particularly myasthenia gravis and Alzheimer's disease.
format Review
author Pratchayasakul W.
Pongchaidecha A.
Chattipakorn N.
Chattipakorn S.
spellingShingle Pratchayasakul W.
Pongchaidecha A.
Chattipakorn N.
Chattipakorn S.
Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
author_facet Pratchayasakul W.
Pongchaidecha A.
Chattipakorn N.
Chattipakorn S.
author_sort Pratchayasakul W.
title Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_short Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_full Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_fullStr Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_full_unstemmed Ethnobotany and ethnopharmacology of Tabernaemontana divaricata
title_sort ethnobotany and ethnopharmacology of tabernaemontana divaricata
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-51349097371&partnerID=40&md5=b9fb957ef51f29ae44d990be182f8c87
http://cmuir.cmu.ac.th/handle/6653943832/1026
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