Cleft lip with cleft palate, ankyloglossia, and hypodontia are associated with TBX22 mutations

• Main Authors: Kantaputra P.N., Paramee M., Kaewkhampa A., Hoshino A., Lees M., McEntagart M., Masrour N., Moore G.E., Pauws E., Stanier P.
• 格式: Conference or Workshop Item
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-79954578070&partnerID=40&md5=c7eac0c892d354568b826f3eb414e345; http://www.ncbi.nlm.nih.gov/pubmed/21248356; http://cmuir.cmu.ac.th/handle/6653943832/1050
• 機構: Chiang Mai University

X-linked cleft palate and ankyloglossia (CPX) are caused by mutations in the TBX22 transcription factor. To investigate whether patients with ankyloglossia alone or in the presence of other craniofacial features including hypodontia or CLP might be caused by TBX22 mutations, we analyzed 45 Thai pati...