Involvement of P2X7 purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblasts

• المؤلفون الرئيسيون: Montreekachon P., Chotjumlong P., Bolscher J.G.M., Nazmi K., Reutrakul V., Krisanaprakornkit S.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-79954880573&partnerID=40&md5=f7d983f39f19b3901dd8eb263918312e; http://cmuir.cmu.ac.th/handle/6653943832/1127
• المؤسسة: Chiang Mai University

Background and Objective: The antimicrobial peptide LL-37, derived from human neutrophils, can directly chemoattract leukocytes and up-regulate the expression of several immune-related genes in various cell types. In this study, we wanted to determine the immunoregulatory effect of LL-37 on interleu...