Involvement of P2X<inf>7</inf>purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblasts

Background and Objective: The antimicrobial peptide LL-37, derived from human neutrophils, can directly chemoattract leukocytes and up-regulate the expression of several immune-related genes in various cell types. In this study, we wanted to determine the immunoregulatory effect of LL-37 on interleu...

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Bibliographic Details
Main Authors: P. Montreekachon, P. Chotjumlong, J. G.M. Bolscher, K. Nazmi, V. Reutrakul, S. Krisanaprakornkit
Other Authors: Chiang Mai University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/11830
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Institution: Mahidol University