The antimicrobial peptide, LL-37, inhibits in vitro osteoclastogenesis

• Main Authors: Supanchart C., Thawanaphong S., Makeudom A., Bolscher J.G., Nazmi K., Kornak U., Krisanaprakornkit S.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84867728779&partnerID=40&md5=fbe2565f1947add9f29b2b13b1eed73d; http://cmuir.cmu.ac.th/handle/6653943832/1147
• Institution: Chiang Mai University

Uncoupled bone resorption leads to net alveolar bone loss in periodontitis. The deficiency of LL-37, the only human antimicrobial peptide in the cathelicidin family, in patients with aggressive periodontitis suggests that LL-37 may play a pivotal role in the inhibition of alveolar bone destruction i...