Fed-batch optimization of recombinant α-amylase production by Bacillus subtilis using a modified Markov Chain monte carlo technique

• المؤلفون الرئيسيون: Skolpap W., Nuchprayoon S., Scharer J.M., Grisdanurak N., Douglas P.L., Moo-Young M.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-52349110872&partnerID=40&md5=60050063127f8444d45acc7fc2313841; http://cmuir.cmu.ac.th/handle/6653943832/1394
• المؤسسة: Chiang Mai University

A modified Markov Chain Monte Carlo (MCMC) searching procedure was developed to search for an optimal set of decision variables and optimal feed rate trajectories for recombinant α-amylase expression by Bacillus subtilis ATCC 6051a. The bacterium also synthesizes proteases as undesirable products in...