In vivo identification of Langerhans and related dendritic cells infected with HIV-1 subtype E in vaginal mucosa of asymptomatic patients

• Main Authors: Bhoopat L., Eiangleng L., Rugpao S., Frankel S.S., Weissman D., Lekawanvijit S., Petchjom S., Thorner P., Bhoopat T.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035217649&partnerID=40&md5=70847f961e67a2404ea8fd3ba29a3496; http://www.ncbi.nlm.nih.gov/pubmed/11743049; http://cmuir.cmu.ac.th/handle/6653943832/1672
• Institution: Chiang Mai University

In Thailand, the predominant HIV subtype is E, rather than Subtype B as in North America and Europe, and the predominant mode of transmission is heterosexual contact. Subtype E has the ability to replicate in vitro in Langerhans cells. We hypothesized that this cell type might constitute a reservoir...