Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis

• Main Authors: Solomon M.M., Lama J.R., Glidden D.V., Mulligan K., McMahan V., Liu A.Y., Vicente Guanira J., Veloso V.G., Mayer K.H., Chariyalertsak S., Schechter M., Bekker L.-G., Georges Kallas E., Burns D.N., Grant R.M.
• Format: Article
• Language: English
• Published: Lippincott Williams and Wilkins 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84898016347&partnerID=40&md5=8de0abed92e3316d3c8a5275b21d281f; http://cmuir.cmu.ac.th/handle/6653943832/1737
• Institution: Chiang Mai University

Objective: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis decreases sexual acquisition of HIV infection. We sought to evaluate the renal safety of TDF in HIV-uninfected persons. Design and methods: The Iniciativa Profilaxis Pre-Exposición (iPrEx) study randomly assigned 2499 HIV-serone...