Combined vildagliptin and metformin exert better cardioprotection than monotherapy against ischemia-reperfusion injury in obese-insulin resistant rats

Background: Obese-insulin resistance caused by long-term high-fat diet (HFD) consumption is associated with left ventricular (LV) dysfunction and increased risk of myocardial infarction. Metformin and vildagliptin have been shown to exert cardioprotective effects. However, the effect of these drugs...

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Main Authors: Apaijai N., Chinda K., Palee S., Chattipakorn S., Chattipakorn N.
格式: Article
語言:English
出版: Public Library of Science 2014
在線閱讀:http://www.scopus.com/inward/record.url?eid=2-s2.0-84904540452&partnerID=40&md5=b2b2f6dfe4fc39cfecbdfaedc5688389
http://cmuir.cmu.ac.th/handle/6653943832/1768
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機構: Chiang Mai University
語言: English