Combined vildagliptin and metformin exert better cardioprotection than monotherapy against ischemia-reperfusion injury in obese-insulin resistant rats

Background: Obese-insulin resistance caused by long-term high-fat diet (HFD) consumption is associated with left ventricular (LV) dysfunction and increased risk of myocardial infarction. Metformin and vildagliptin have been shown to exert cardioprotective effects. However, the effect of these drugs...

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Bibliographic Details
Main Authors: Apaijai N., Chinda K., Palee S., Chattipakorn S., Chattipakorn N.
Format: Article
Language:English
Published: Public Library of Science 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84904540452&partnerID=40&md5=b2b2f6dfe4fc39cfecbdfaedc5688389
http://cmuir.cmu.ac.th/handle/6653943832/995
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Institution: Chiang Mai University
Language: English