Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.

The aim of this study was to identify the factors affecting incomplete excision after the loop electrosurgical excision procedure (LEEP) for evaluation and treatment of cervical neoplasia. Patients with abnormal cervical cytology who underwent colposcopy and LEEP at Chiang Mai University Hospital be...

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Main Authors: Kietpeerakool C., Srisomboon J., Ratchusiri K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-33646705905&partnerID=40&md5=0369cf80eb8e91cdb1787551d6770731
http://cmuir.cmu.ac.th/handle/6653943832/1831
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-18312014-08-30T02:00:10Z Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia. Kietpeerakool C. Srisomboon J. Ratchusiri K. The aim of this study was to identify the factors affecting incomplete excision after the loop electrosurgical excision procedure (LEEP) for evaluation and treatment of cervical neoplasia. Patients with abnormal cervical cytology who underwent colposcopy and LEEP at Chiang Mai University Hospital between October 2004 and July 2005, were retrospectively evaluated. During the study period, 201 patients were eligible for analysis. All cone margin involvement was observed in 44% of the patients (95% CI, 37.3-51.4). Multivariate analysis revealed that invasive cancer on cytology (adjusted odds ratio [aOR] =3.05, 95% confidence interval [CI] =1.03 to 9.00; P=0.02), invasive cancer on LEEP histopathology (aOR=9.73, 95%CI =3.95 to 23.9; P<0.001), and a cone length of less than 10 mm (aOR =1.95, 95%CI =1.04 to 3.66; P =0.03) were significant predictors for any cone margin involvement. For endocervical margin involvement, postmenopausal status and a cone length of less than 10 mm were significant predictors of incomplete excision. In contrast to endocervical margin involvement, postmenopausal status was significantly associated with a decreased risk of ectocervical margin involvement. Invasive cancer on histopathology was a significant predictor of both ecto- and endocervical margin involvement. In conclusion, invasive cancer either on cytology or LEEP specimens and a cone length of less than 10 mm are significant predictors of incomplete excision. 2014-08-30T02:00:10Z 2014-08-30T02:00:10Z 2005 Article 15137368 16435996 http://www.scopus.com/inward/record.url?eid=2-s2.0-33646705905&partnerID=40&md5=0369cf80eb8e91cdb1787551d6770731 http://cmuir.cmu.ac.th/handle/6653943832/1831 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The aim of this study was to identify the factors affecting incomplete excision after the loop electrosurgical excision procedure (LEEP) for evaluation and treatment of cervical neoplasia. Patients with abnormal cervical cytology who underwent colposcopy and LEEP at Chiang Mai University Hospital between October 2004 and July 2005, were retrospectively evaluated. During the study period, 201 patients were eligible for analysis. All cone margin involvement was observed in 44% of the patients (95% CI, 37.3-51.4). Multivariate analysis revealed that invasive cancer on cytology (adjusted odds ratio [aOR] =3.05, 95% confidence interval [CI] =1.03 to 9.00; P=0.02), invasive cancer on LEEP histopathology (aOR=9.73, 95%CI =3.95 to 23.9; P<0.001), and a cone length of less than 10 mm (aOR =1.95, 95%CI =1.04 to 3.66; P =0.03) were significant predictors for any cone margin involvement. For endocervical margin involvement, postmenopausal status and a cone length of less than 10 mm were significant predictors of incomplete excision. In contrast to endocervical margin involvement, postmenopausal status was significantly associated with a decreased risk of ectocervical margin involvement. Invasive cancer on histopathology was a significant predictor of both ecto- and endocervical margin involvement. In conclusion, invasive cancer either on cytology or LEEP specimens and a cone length of less than 10 mm are significant predictors of incomplete excision.
format Article
author Kietpeerakool C.
Srisomboon J.
Ratchusiri K.
spellingShingle Kietpeerakool C.
Srisomboon J.
Ratchusiri K.
Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
author_facet Kietpeerakool C.
Srisomboon J.
Ratchusiri K.
author_sort Kietpeerakool C.
title Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
title_short Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
title_full Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
title_fullStr Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
title_full_unstemmed Clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
title_sort clinicopathologic predictors of incomplete excision after loop electrosurgical excision for cervical preneoplasia.
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-33646705905&partnerID=40&md5=0369cf80eb8e91cdb1787551d6770731
http://cmuir.cmu.ac.th/handle/6653943832/1831
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