Antimutagenicity and DT-diaphorase inducing activity of Gynostemma pentaphyllum Makino extract

• Main Authors: Kulwat C., Lertprasertsuke N., Leechanachai P., Kongtawelert P., Vinitketkumnuen U.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-27244442105&partnerID=40&md5=977d1010c6c14648c689461c0e1d3d4e; http://www.ncbi.nlm.nih.gov/pubmed/16167531; http://cmuir.cmu.ac.th/handle/6653943832/1866
• Institution: Chiang Mai University

The hot water extract of the herbal tea, Gynostemma pentaphyllum Makino, was not found to be mutagenic in Salmonella mutation assay with or without metabolic activation. However, the extract had both DT-diaphorase inducing activity in the murine hepatoma (Hepa1c1c7) cell line and antimutagenic prope...