Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation

The objective of this study was to evaluate the outcomes of stages IB-IIA cervical cancer patients whose radical hysterectomy (RH) was abandoned for positive pelvic nodes detected during the operation compared with those found to have positive nodes after the operation. Among 242 patients with plann...

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Main Authors: Suprasert P., Srisomboon J., Charoenkwan K., Siriaungul S., Khunamornpong S., Siriaree S., Phongnarisorn C., Lorvidhaya V.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-18944396120&partnerID=40&md5=ecfbf1b2abfb222f8316c398af6f6327
http://www.ncbi.nlm.nih.gov/pubmed/15882176
http://cmuir.cmu.ac.th/handle/6653943832/1915
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-19152014-08-30T02:00:15Z Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation Suprasert P. Srisomboon J. Charoenkwan K. Siriaungul S. Khunamornpong S. Siriaree S. Phongnarisorn C. Lorvidhaya V. The objective of this study was to evaluate the outcomes of stages IB-IIA cervical cancer patients whose radical hysterectomy (RH) was abandoned for positive pelvic nodes detected during the operation compared with those found to have positive nodes after the operation. Among 242 patients with planned RH and pelvic lymphadenectomy (RHPL) for stages IB-IIA cervical cancer, 23 (9.5%) had grossly positive nodes. RH was abandoned, and complete pelvic lymphadenectomy was performed. Of these 23 patients, 22 received adjuvant chemoradiation, and the remaining 1 received adjuvant radiation. Four patients with positive para-aortic nodes were additionally treated with extended-field irradiation. When compared with 35 patients whose positive nodes were detected after the operation, there were significant differences regarding number of positive nodes and number of patients receiving extended-field irradiation. Complications in both groups were not significantly different, but the 2-year disease-free survival was significantly lower in the abandoned RH group compared with that of the RHPL group (58.5% versus 93.5%, P = 0.01). In conclusion, the survival of stages IB-IIA cervical cancer patients whose RH was abandoned for grossly positive pelvic nodes was significantly worse than that of patients whose node metastasis was identified after the operation. This is because the abandoned RH group had worse prognostic factors. © 2005 IGCS. 2014-08-30T02:00:15Z 2014-08-30T02:00:15Z 2005 Article 1048891X 10.1111/j.1525-1438.2005.15315.x 15882176 IJGCE http://www.scopus.com/inward/record.url?eid=2-s2.0-18944396120&partnerID=40&md5=ecfbf1b2abfb222f8316c398af6f6327 http://www.ncbi.nlm.nih.gov/pubmed/15882176 http://cmuir.cmu.ac.th/handle/6653943832/1915 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The objective of this study was to evaluate the outcomes of stages IB-IIA cervical cancer patients whose radical hysterectomy (RH) was abandoned for positive pelvic nodes detected during the operation compared with those found to have positive nodes after the operation. Among 242 patients with planned RH and pelvic lymphadenectomy (RHPL) for stages IB-IIA cervical cancer, 23 (9.5%) had grossly positive nodes. RH was abandoned, and complete pelvic lymphadenectomy was performed. Of these 23 patients, 22 received adjuvant chemoradiation, and the remaining 1 received adjuvant radiation. Four patients with positive para-aortic nodes were additionally treated with extended-field irradiation. When compared with 35 patients whose positive nodes were detected after the operation, there were significant differences regarding number of positive nodes and number of patients receiving extended-field irradiation. Complications in both groups were not significantly different, but the 2-year disease-free survival was significantly lower in the abandoned RH group compared with that of the RHPL group (58.5% versus 93.5%, P = 0.01). In conclusion, the survival of stages IB-IIA cervical cancer patients whose RH was abandoned for grossly positive pelvic nodes was significantly worse than that of patients whose node metastasis was identified after the operation. This is because the abandoned RH group had worse prognostic factors. © 2005 IGCS.
format Article
author Suprasert P.
Srisomboon J.
Charoenkwan K.
Siriaungul S.
Khunamornpong S.
Siriaree S.
Phongnarisorn C.
Lorvidhaya V.
spellingShingle Suprasert P.
Srisomboon J.
Charoenkwan K.
Siriaungul S.
Khunamornpong S.
Siriaree S.
Phongnarisorn C.
Lorvidhaya V.
Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
author_facet Suprasert P.
Srisomboon J.
Charoenkwan K.
Siriaungul S.
Khunamornpong S.
Siriaree S.
Phongnarisorn C.
Lorvidhaya V.
author_sort Suprasert P.
title Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
title_short Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
title_full Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
title_fullStr Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
title_full_unstemmed Outcomes of abandoned radical hysterectomy in patients with stages IB-IIA cervical cancer found to have positive nodes during the operation
title_sort outcomes of abandoned radical hysterectomy in patients with stages ib-iia cervical cancer found to have positive nodes during the operation
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-18944396120&partnerID=40&md5=ecfbf1b2abfb222f8316c398af6f6327
http://www.ncbi.nlm.nih.gov/pubmed/15882176
http://cmuir.cmu.ac.th/handle/6653943832/1915
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