Fetal loss rate associated with cordocentesis at midgestation

OBJECTIVE: The aim of this study was to assess the risk of fetal loss attributable to cordocentesis at midgestation. STUDY DESIGN: A cohort study was conducted during the period 1989-1999. Women undergoing cordocentesis between 16 and 24 weeks' gestation with singleton pregnancies without obvio...

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Main Authors: Tongsong T., Wanapirak C., Kunavikatikul C., Sirirchotiyakul S., Piyamongkol W., Chanprapaph P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-0035077023&partnerID=40&md5=976861ed660ce1e433a9cdf52895591d
http://www.ncbi.nlm.nih.gov/pubmed/11262478
http://cmuir.cmu.ac.th/handle/6653943832/1942
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-19422014-08-30T02:00:17Z Fetal loss rate associated with cordocentesis at midgestation Tongsong T. Wanapirak C. Kunavikatikul C. Sirirchotiyakul S. Piyamongkol W. Chanprapaph P. OBJECTIVE: The aim of this study was to assess the risk of fetal loss attributable to cordocentesis at midgestation. STUDY DESIGN: A cohort study was conducted during the period 1989-1999. Women undergoing cordocentesis between 16 and 24 weeks' gestation with singleton pregnancies without obvious fetal anomaly were recruited into the study group. The control subjects were selected prospectively on a one-to-one basis with strict matching for maternal age, parity, gestational age at recruitment, and socioeconomic status. Both groups were prospectively followed up until delivery. RESULTS: A total of 1281 women with successful cordocentesis and their matched control subjects were recruited to the study. After exclusion of some pairs because of loss to follow-up or fetal malformations or severe disease necessitating termination of pregnancy, 1020 matched pairs were available to be compared with respect to fetal loss rate and pregnancy outcomes. The fetal loss rate was significantly higher among the study group (3.2% vs 1.8%; P < .05, McNemar test). However, there were no significant differences in other obstetric complications between the study and control groups. CONCLUSION: The incremental fetal loss rate associated with cordocentesis at midgestation was about 1.4%. 2014-08-30T02:00:17Z 2014-08-30T02:00:17Z 2001 Article 00029378 10.1067/mob.2001.111716 11262478 AJOGA http://www.scopus.com/inward/record.url?eid=2-s2.0-0035077023&partnerID=40&md5=976861ed660ce1e433a9cdf52895591d http://www.ncbi.nlm.nih.gov/pubmed/11262478 http://cmuir.cmu.ac.th/handle/6653943832/1942 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description OBJECTIVE: The aim of this study was to assess the risk of fetal loss attributable to cordocentesis at midgestation. STUDY DESIGN: A cohort study was conducted during the period 1989-1999. Women undergoing cordocentesis between 16 and 24 weeks' gestation with singleton pregnancies without obvious fetal anomaly were recruited into the study group. The control subjects were selected prospectively on a one-to-one basis with strict matching for maternal age, parity, gestational age at recruitment, and socioeconomic status. Both groups were prospectively followed up until delivery. RESULTS: A total of 1281 women with successful cordocentesis and their matched control subjects were recruited to the study. After exclusion of some pairs because of loss to follow-up or fetal malformations or severe disease necessitating termination of pregnancy, 1020 matched pairs were available to be compared with respect to fetal loss rate and pregnancy outcomes. The fetal loss rate was significantly higher among the study group (3.2% vs 1.8%; P < .05, McNemar test). However, there were no significant differences in other obstetric complications between the study and control groups. CONCLUSION: The incremental fetal loss rate associated with cordocentesis at midgestation was about 1.4%.
format Article
author Tongsong T.
Wanapirak C.
Kunavikatikul C.
Sirirchotiyakul S.
Piyamongkol W.
Chanprapaph P.
spellingShingle Tongsong T.
Wanapirak C.
Kunavikatikul C.
Sirirchotiyakul S.
Piyamongkol W.
Chanprapaph P.
Fetal loss rate associated with cordocentesis at midgestation
author_facet Tongsong T.
Wanapirak C.
Kunavikatikul C.
Sirirchotiyakul S.
Piyamongkol W.
Chanprapaph P.
author_sort Tongsong T.
title Fetal loss rate associated with cordocentesis at midgestation
title_short Fetal loss rate associated with cordocentesis at midgestation
title_full Fetal loss rate associated with cordocentesis at midgestation
title_fullStr Fetal loss rate associated with cordocentesis at midgestation
title_full_unstemmed Fetal loss rate associated with cordocentesis at midgestation
title_sort fetal loss rate associated with cordocentesis at midgestation
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-0035077023&partnerID=40&md5=976861ed660ce1e433a9cdf52895591d
http://www.ncbi.nlm.nih.gov/pubmed/11262478
http://cmuir.cmu.ac.th/handle/6653943832/1942
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