Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis

Background: Estimation of glomerular filtration rate (GFR) is usually determined from 24-hour urine collection, but it is time-consuming, and difficult in clinical practice. The authors attempted to select an accurate and safe, but more convenient test to obtain an estimated GFR. Objective: To compa...

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Main Authors: Satirapoj B., Supasyndh O., Patumanond J., Choovichian P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-33750970890&partnerID=40&md5=899916568ad023a65067a674e04d1201
http://cmuir.cmu.ac.th/handle/6653943832/2039
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spelling th-cmuir.6653943832-20392014-08-30T02:00:24Z Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis Satirapoj B. Supasyndh O. Patumanond J. Choovichian P. Background: Estimation of glomerular filtration rate (GFR) is usually determined from 24-hour urine collection, but it is time-consuming, and difficult in clinical practice. The authors attempted to select an accurate and safe, but more convenient test to obtain an estimated GFR. Objective: To compare estimation of GFR by Bioelectrical impedance analysis (BIA) with GFR calculated by 24-hour urine averaged creatinine clearance and urea clearance (Ccr-Cu-GFR). Material and Method: The authors examined 79 non-diabetic chronic kidney disease (CKD) patients that had estimated GFR between 15 and 89 ml/min/1.73 m2. Subjects were categorized into three subgroups according to K/DOQI-CKD classification: GFR of 60-89 ml/min/1.73m2 (stage 2, 5 subjects), 30-59 ml/min/ 1.73m2 (stage 3, 31 subjects), and 15-29 ml/min/1.73m2 (stage 4, 43 subjects). Results: The mean value of Ccr-Cu-GFR was 33.79 ± 14.78 ml/min/1.73 m2 and GFR by BIA (BIA-GFR), 34.63 ± 14.86 ml/min/1.73 m2 with no overall statistical differences (p = 0.838). In stage 3 CKD patients, the mean BIA-GFR and Ccr-Cu-GFR were similar (38.84 ± 12.47 vs 41.16 ± 9.17, p = 0.399) while in stage 2 CKD, BIAGFR tended to underestimate (63.50 ± 19.35 vs 70.94 ± 7.82, p = 0.407) and in stage 4 CKD, BIA-GFR significantly overestimated Ccr-Cu-GFR (27.31 ± 9.11 vs 23.76 ± 5.68, p = 0.040). Conclusion: The findings suggest that BIA-GFR in non-diabetic CKD patients closely resembled with Ccr-Cu-GFR especially in stage 3 CKD patients. BIA-GFR may be considered as a more convenient test for an assessment of GFR in non-diabetic CKD patients. 2014-08-30T02:00:24Z 2014-08-30T02:00:24Z 2006 Article 01252208 17128831 JMTHB http://www.scopus.com/inward/record.url?eid=2-s2.0-33750970890&partnerID=40&md5=899916568ad023a65067a674e04d1201 http://cmuir.cmu.ac.th/handle/6653943832/2039 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Background: Estimation of glomerular filtration rate (GFR) is usually determined from 24-hour urine collection, but it is time-consuming, and difficult in clinical practice. The authors attempted to select an accurate and safe, but more convenient test to obtain an estimated GFR. Objective: To compare estimation of GFR by Bioelectrical impedance analysis (BIA) with GFR calculated by 24-hour urine averaged creatinine clearance and urea clearance (Ccr-Cu-GFR). Material and Method: The authors examined 79 non-diabetic chronic kidney disease (CKD) patients that had estimated GFR between 15 and 89 ml/min/1.73 m2. Subjects were categorized into three subgroups according to K/DOQI-CKD classification: GFR of 60-89 ml/min/1.73m2 (stage 2, 5 subjects), 30-59 ml/min/ 1.73m2 (stage 3, 31 subjects), and 15-29 ml/min/1.73m2 (stage 4, 43 subjects). Results: The mean value of Ccr-Cu-GFR was 33.79 ± 14.78 ml/min/1.73 m2 and GFR by BIA (BIA-GFR), 34.63 ± 14.86 ml/min/1.73 m2 with no overall statistical differences (p = 0.838). In stage 3 CKD patients, the mean BIA-GFR and Ccr-Cu-GFR were similar (38.84 ± 12.47 vs 41.16 ± 9.17, p = 0.399) while in stage 2 CKD, BIAGFR tended to underestimate (63.50 ± 19.35 vs 70.94 ± 7.82, p = 0.407) and in stage 4 CKD, BIA-GFR significantly overestimated Ccr-Cu-GFR (27.31 ± 9.11 vs 23.76 ± 5.68, p = 0.040). Conclusion: The findings suggest that BIA-GFR in non-diabetic CKD patients closely resembled with Ccr-Cu-GFR especially in stage 3 CKD patients. BIA-GFR may be considered as a more convenient test for an assessment of GFR in non-diabetic CKD patients.
format Article
author Satirapoj B.
Supasyndh O.
Patumanond J.
Choovichian P.
spellingShingle Satirapoj B.
Supasyndh O.
Patumanond J.
Choovichian P.
Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
author_facet Satirapoj B.
Supasyndh O.
Patumanond J.
Choovichian P.
author_sort Satirapoj B.
title Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
title_short Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
title_full Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
title_fullStr Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
title_full_unstemmed Estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
title_sort estimating glomerular filtration rate in asian patients with chronic kidney diseases from bioelectrical impedance analysis
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-33750970890&partnerID=40&md5=899916568ad023a65067a674e04d1201
http://cmuir.cmu.ac.th/handle/6653943832/2039
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