Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand
We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell p...
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2014
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th-cmuir.6653943832-21252014-08-30T02:00:30Z Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand Puthanakit T. Aurpibul L. Oberdorfer P. Akarathum N. Kanjanavanit S. Wannarit P. Sirisanthana T. Sirisanthana V. We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell percentage increased from 5.3% to 26.6%. HAART is effective for HIV-infected children in this resource-poor setting despite initiation of treatment in the advanced stage of disease. © 2007 Lippincott Williams & Wilkins, Inc. 2014-08-30T02:00:30Z 2014-08-30T02:00:30Z 2007 Article 08913668 10.1097/INF.0b013e318125720a 17901804 PIDJE http://www.scopus.com/inward/record.url?eid=2-s2.0-34848919230&partnerID=40&md5=40e08c98baf0df7f6a0d8cf45f97d5c2 http://www.ncbi.nlm.nih.gov/pubmed/17901804 http://cmuir.cmu.ac.th/handle/6653943832/2125 English |
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We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell percentage increased from 5.3% to 26.6%. HAART is effective for HIV-infected children in this resource-poor setting despite initiation of treatment in the advanced stage of disease. © 2007 Lippincott Williams & Wilkins, Inc. |
| format |
Article |
| author |
Puthanakit T. Aurpibul L. Oberdorfer P. Akarathum N. Kanjanavanit S. Wannarit P. Sirisanthana T. Sirisanthana V. |
| spellingShingle |
Puthanakit T. Aurpibul L. Oberdorfer P. Akarathum N. Kanjanavanit S. Wannarit P. Sirisanthana T. Sirisanthana V. Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| author_facet |
Puthanakit T. Aurpibul L. Oberdorfer P. Akarathum N. Kanjanavanit S. Wannarit P. Sirisanthana T. Sirisanthana V. |
| author_sort |
Puthanakit T. |
| title |
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| title_short |
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| title_full |
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| title_fullStr |
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| title_full_unstemmed |
Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand |
| title_sort |
sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in thailand |
| publishDate |
2014 |
| url |
http://www.scopus.com/inward/record.url?eid=2-s2.0-34848919230&partnerID=40&md5=40e08c98baf0df7f6a0d8cf45f97d5c2 http://www.ncbi.nlm.nih.gov/pubmed/17901804 http://cmuir.cmu.ac.th/handle/6653943832/2125 |
| _version_ |
1681419799564910592 |