Effect of Stemona curtisii root extract on P-glycoprotein and MRP-1 function in multidrug-resistant cancer cells

Multidrug resistance (MDR) is the result of overexpression of membrane bound proteins that efflux chemotherapeutic drugs from the cells. Two proteins, P-glycoprotein (P-gp) and multidrug-resistance associated protein-1 (MRP-1) efflux chemotherapeutic agents out of the cancer cell that decrease intra...

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Bibliographic Details
Main Authors: Limtrakul P., Siwanon S., Yodkeeree S., Duangrat C.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-34249306886&partnerID=40&md5=de3346d8a68f3f3c217562a34bbf2488
http://www.ncbi.nlm.nih.gov/pubmed/17467965
http://cmuir.cmu.ac.th/handle/6653943832/2191
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Institution: Chiang Mai University
Language: English