Membrane topology of murine coronavirus replicase nonstructural protein 3

• Main Authors: Kanjanahaluethai A., Chen Z., Jukneliene D., Baker S.C.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-34247163017&partnerID=40&md5=454dbf593759355cb8d2dc76283ae0c3; http://cmuir.cmu.ac.th/handle/6653943832/2210
• Institution: Chiang Mai University

Mouse hepatitis virus (MHV) is a member of the family Coronaviridae. These positive strand RNA viruses encode a replicase polyprotein that is processed into 16 nonstructural proteins (nsps). The nsps assemble with membranes to generate double membrane vesicles, which are the sites of viral RNA synth...