Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery

Objective: To compare the efficacy of dexpanthenol spray and saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery (ESS). Material and Method: One hundred twenty eight sinusitis patients undergoing ESS were randomly allocated to receive dexpanthenol spr...

Full description

Saved in:
Bibliographic Details
Main Authors: Fooanant S., Chaiyasate S., Roongrotwattanasiri K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-55249111297&partnerID=40&md5=8a7c0ea84baf2a16281e2873dfae2880
http://www.ncbi.nlm.nih.gov/pubmed/18972900
http://cmuir.cmu.ac.th/handle/6653943832/2367
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
Language: English
id th-cmuir.6653943832-2367
record_format dspace
spelling th-cmuir.6653943832-23672014-08-30T02:00:46Z Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery Fooanant S. Chaiyasate S. Roongrotwattanasiri K. Objective: To compare the efficacy of dexpanthenol spray and saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery (ESS). Material and Method: One hundred twenty eight sinusitis patients undergoing ESS were randomly allocated to receive dexpanthenol spray (Mar plus) or saline irrigation twice a day for 4 weeks after the operation. Total nasal symptom score, crusting, infection, compliance, and patient satisfaction were evaluated at 1, 2-3, 4-6, and 12 weeks. Mucociliary clearance was assessed with the saccharin test before ESS and at the last visit. One hundred ten patients remained at the present study termination. Chi-square test and Mann-Whitney U test were employed. Results: Total nasal symptom score, mucociliary clearance, and infection improved in both groups after the operation. The dexpanthenol group resulted in a better mucociliary clearance than saline irrigation (9.93 ± 6.04 vs. 12.38 ± 9.32 min, p = 0.43). Saline irrigation resulted in a greater reduction of post nasal drip than dexpanthenol at the first visit (74% vs. 87%, p = 0.04). Compliance and patient satisfaction were comparable. Conclusion: The efficacy of dexpanthenol was comparable to nasal saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery. Dexpanthenol is an alternative treatment, which may be useful in young children and complicated cases. 2014-08-30T02:00:46Z 2014-08-30T02:00:46Z 2008 Article 01252208 18972900 JMTHB http://www.scopus.com/inward/record.url?eid=2-s2.0-55249111297&partnerID=40&md5=8a7c0ea84baf2a16281e2873dfae2880 http://www.ncbi.nlm.nih.gov/pubmed/18972900 http://cmuir.cmu.ac.th/handle/6653943832/2367 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Objective: To compare the efficacy of dexpanthenol spray and saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery (ESS). Material and Method: One hundred twenty eight sinusitis patients undergoing ESS were randomly allocated to receive dexpanthenol spray (Mar plus) or saline irrigation twice a day for 4 weeks after the operation. Total nasal symptom score, crusting, infection, compliance, and patient satisfaction were evaluated at 1, 2-3, 4-6, and 12 weeks. Mucociliary clearance was assessed with the saccharin test before ESS and at the last visit. One hundred ten patients remained at the present study termination. Chi-square test and Mann-Whitney U test were employed. Results: Total nasal symptom score, mucociliary clearance, and infection improved in both groups after the operation. The dexpanthenol group resulted in a better mucociliary clearance than saline irrigation (9.93 ± 6.04 vs. 12.38 ± 9.32 min, p = 0.43). Saline irrigation resulted in a greater reduction of post nasal drip than dexpanthenol at the first visit (74% vs. 87%, p = 0.04). Compliance and patient satisfaction were comparable. Conclusion: The efficacy of dexpanthenol was comparable to nasal saline irrigation in the postoperative care of sinusitis patients following endoscopic sinus surgery. Dexpanthenol is an alternative treatment, which may be useful in young children and complicated cases.
format Article
author Fooanant S.
Chaiyasate S.
Roongrotwattanasiri K.
spellingShingle Fooanant S.
Chaiyasate S.
Roongrotwattanasiri K.
Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
author_facet Fooanant S.
Chaiyasate S.
Roongrotwattanasiri K.
author_sort Fooanant S.
title Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
title_short Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
title_full Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
title_fullStr Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
title_full_unstemmed Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
title_sort comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-55249111297&partnerID=40&md5=8a7c0ea84baf2a16281e2873dfae2880
http://www.ncbi.nlm.nih.gov/pubmed/18972900
http://cmuir.cmu.ac.th/handle/6653943832/2367
_version_ 1681419845360418816