Modification of solid phase red cell adherence assay for the detection of platelet antibodies in patients with thrombocytopenia

• Main Authors: Vongchan P., Nawarawong W., Linhardt R.J.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-51349137119&partnerID=40&md5=afe977d72a0ba182ef3d94e82c008f2a; http://www.ncbi.nlm.nih.gov/pubmed/18701420; http://cmuir.cmu.ac.th/handle/6653943832/2385
• Institution: Chiang Mai University

Platelet refractoriness is caused by HLA antibodies and platelet-specific antibodies. Current methods used to detect antiplatelet antibodies have limitations. Solid phase red cell adherence (SPRCA) lacks sensitivity and requires a second assay using chloroquine-treated intact platelets to specify th...