Novel anti-dengue monoclonal antibody recognizing conformational structure of the prM-E heterodimeric complex of dengue virus

• Main Authors: Puttikhunt C., Keelapang P., Khemnu N., Sittisombut N., Kasinrerk W., Malasit P.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-36849036001&partnerID=40&md5=0bfde4d8356d2887e050619f154e3974; http://cmuir.cmu.ac.th/handle/6653943832/2499
• 機構: Chiang Mai University

An interaction between the premembrane (prM) and envelope (E) glycoproteins as prM-E heterodimer is required for proper folding and transport of E during the formation and release of new flaviviral progeny. More evidence, however, is needed to confirm this interaction of prM and E during dengue viru...