Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy

• Main Authors: Kumthip K., Pantip C., Chusri P., Thongsawat S., O'Brien A., Nelson K.E., Maneekarn N.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-79952652957&partnerID=40&md5=562a143a928434f2163d60e22fbe5402; http://www.ncbi.nlm.nih.gov/pubmed/20955493; http://cmuir.cmu.ac.th/handle/6653943832/2675
• Institution: Chiang Mai University

Several studies have reported correlation between mutations in core and NS5A proteins of hepatitis C virus (HCV) and response to interferon (IFN) therapy. In particular, mutations in NS5A protein have been shown to correlate with responsiveness to IFN treatment of HCV-1b in Japanese patients. This s...