Recurrent tibial intra-cortical osteosarcoma: A case report and review of the literature

• Main Authors: Arpornchayanon O., Leerapun T., Sivasomboon C., Settakorn J., Sugandhavesa N., Pruksakorn D.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-79952318325&partnerID=40&md5=396f5d05c7ed21ba8337137a88f749f3; http://www.ncbi.nlm.nih.gov/pubmed/21385347; http://cmuir.cmu.ac.th/handle/6653943832/2685
• Institution: Chiang Mai University

Introduction. Intra-cortical osteosarcoma is the rarest subtype of osseous-producing tumor. Most reported cases present a low-grade histology with slow progression and good oncological control after adequate treatment. In this report, we describe a case and review the literature to propose adequate treatment. Case presentation. We present the case of a 21-year-old Thai woman who was thought to have an intra-cortical osteosarcoma of the right tibia. We performed a wide resection and reconstruction with bone transportation using an Ilizarov external fixator. The tumor recurred five years later at the same site with a similar histology. We performed a new resection and reconstruction by ankle arthrodesis with adjuvant chemotherapy. At the last follow-up, she had remained active and free from disease for seven years. Conclusion: This case report of recurrent intra-cortical osteosarcoma describes an atypical presentation. The low-grade histology, adequate surgical margin and adjuvant chemotherapy of the recurrent lesion were favorable factors, and our patient has remained free of any tumor recurrence. © 2011 Arpornchayanon et al; licensee BioMed Central Ltd.