Antibody responses to hepatitis A virus vaccination in Thai HIV-infected children with immune recovery after antiretroviral therapy

The prevalence of hepatitis A virus (HAV) protective antibody in 98 Thai HIV-infected children who achieved immune recovery after antiretroviral therapy was 12.2%. After a 2-dose HAV vaccination, 98.8% (85 of 86 children) seroconverted. The geometric mean titer was 520.95 mIU/mL. In a multivariate a...

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Bibliographic Details
Main Authors: Sudjaritruk T., Sirisanthana T., Sirisanthana V.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-79951679948&partnerID=40&md5=9d00b8a32b3e71354e4bb07cb82fdfc8
http://www.ncbi.nlm.nih.gov/pubmed/20856163
http://cmuir.cmu.ac.th/handle/6653943832/2697
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Institution: Chiang Mai University
Language: English
Description
Summary:The prevalence of hepatitis A virus (HAV) protective antibody in 98 Thai HIV-infected children who achieved immune recovery after antiretroviral therapy was 12.2%. After a 2-dose HAV vaccination, 98.8% (85 of 86 children) seroconverted. The geometric mean titer was 520.95 mIU/mL. In a multivariate analysis, female gender, age <12 years and higher CD4 lymphocyte count at enrollment were predicting factors for high (≥250 mIU/mL) HAV antibody response. © 2011 Lippincott Williams & Wilkins, Inc.