Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography
Purpose: To compare the patterns of retinal nerve fiber layer (RNFL) thickness loss in primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) using optical coherence tomography (OCT). Methods: Forty-three participants with PACG and 60 with POAG underwent fast RNFL thickness mea...
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th-cmuir.6653943832-27202014-08-30T02:25:18Z Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography Manassakorn A. Aupapong S. Purpose: To compare the patterns of retinal nerve fiber layer (RNFL) thickness loss in primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) using optical coherence tomography (OCT). Methods: Forty-three participants with PACG and 60 with POAG underwent fast RNFL thickness measurement by OCT. Eyes were classified according to the visual field mean deviation (VF-MD) into mild (>-8 dB), moderate (-8 dB to >-16 dB), and advanced (≤-16 dB) glaucoma subgroups. The raw RNFL thickness data were compared with data from the Thai normative database. Results: Mean (SD) age was 67.0 (9.6) and 64.1 (11.6) years in the PACG and POAG groups, respectively (P = 0.19). In the mild subgroups, a focal RNFL thickness loss was found in the inferior area in the POAG group, but not in the PACG group. The RNFL defect involved sectors 1, 6, and 7 in the moderately advanced disease subgroups of both PACG and POAG and extended through almost all sectors in the advanced disease subgroups. The deepest RNFL defect, -17.25 μm, was found in sector 6 of the mild POAG subgroup, compared with -8.78 μm in the PACG group (P = 0.04). The number of affected points in each sector in the mild subgroups was greater in the POAG group than in the PACG group. Conclusion: Participants with mild POAG had deeper and more localized RNFL defects than did participants with PACG. The pattern was similar in participants with moderate or advanced disease. © 2011 Japanese Ophthalmological Society (JOS). 2014-08-30T02:25:18Z 2014-08-30T02:25:18Z 2011 Article 215155 10.1007/s10384-010-0898-6 21331689 JJOPA http://www.scopus.com/inward/record.url?eid=2-s2.0-79952306406&partnerID=40&md5=9564ec646cf3d845c19b47d7efbc84bb http://www.ncbi.nlm.nih.gov/pubmed/21331689 http://cmuir.cmu.ac.th/handle/6653943832/2720 English |
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Purpose: To compare the patterns of retinal nerve fiber layer (RNFL) thickness loss in primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) using optical coherence tomography (OCT). Methods: Forty-three participants with PACG and 60 with POAG underwent fast RNFL thickness measurement by OCT. Eyes were classified according to the visual field mean deviation (VF-MD) into mild (>-8 dB), moderate (-8 dB to >-16 dB), and advanced (≤-16 dB) glaucoma subgroups. The raw RNFL thickness data were compared with data from the Thai normative database. Results: Mean (SD) age was 67.0 (9.6) and 64.1 (11.6) years in the PACG and POAG groups, respectively (P = 0.19). In the mild subgroups, a focal RNFL thickness loss was found in the inferior area in the POAG group, but not in the PACG group. The RNFL defect involved sectors 1, 6, and 7 in the moderately advanced disease subgroups of both PACG and POAG and extended through almost all sectors in the advanced disease subgroups. The deepest RNFL defect, -17.25 μm, was found in sector 6 of the mild POAG subgroup, compared with -8.78 μm in the PACG group (P = 0.04). The number of affected points in each sector in the mild subgroups was greater in the POAG group than in the PACG group. Conclusion: Participants with mild POAG had deeper and more localized RNFL defects than did participants with PACG. The pattern was similar in participants with moderate or advanced disease. © 2011 Japanese Ophthalmological Society (JOS). |
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Article |
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Manassakorn A. Aupapong S. |
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Manassakorn A. Aupapong S. Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
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Manassakorn A. Aupapong S. |
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Manassakorn A. |
title |
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
title_short |
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
title_full |
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
title_fullStr |
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
title_full_unstemmed |
Retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: A comparison using optical coherence tomography |
title_sort |
retinal nerve fiber layer defect patterns in primary angle-closure and open-angle glaucoma: a comparison using optical coherence tomography |
publishDate |
2014 |
url |
http://www.scopus.com/inward/record.url?eid=2-s2.0-79952306406&partnerID=40&md5=9564ec646cf3d845c19b47d7efbc84bb http://www.ncbi.nlm.nih.gov/pubmed/21331689 http://cmuir.cmu.ac.th/handle/6653943832/2720 |
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