Amniocentesis in twin pregnancies

• Main Authors: Supadilokluck S., Tongprasert F., Tongsong T., Wanapirak C., Piyamongkol W., Sirichotiyakul S., Srisupundit K.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-68149097074&partnerID=40&md5=cc20ba51bfe13b2682ea0419a621a650; http://www.ncbi.nlm.nih.gov/pubmed/19112573; http://cmuir.cmu.ac.th/handle/6653943832/2815
• Institution: Chiang Mai University

Objective: To describe the experiences in diagnostic amniocentesis in twin pregnancies. Methods: The computerized database and medical records of pregnant women attending Maternal Fetal Medicine Unit of the hospital for diagnostic amniocentesis at 16-20 weeks gestation between January 1992 and December 2006 were retrospectively reviewed. Results: During 15 years of experience, 7,890 amniocenteses at 16-20 weeks gestation were performed for prenatal diagnosis, including 174 procedures in 87 twin pregnancies. The mean gestational age at the time of amniocentesis was 17.13 ± 3.35 weeks. Preterm birth rate defined as the delivery before 36 gestational weeks was 36.24%. The total fetal loss rate was 5.17%, however, the procedure related fetal loss within 2 weeks after the procedure was 1.15%. Conclusion: Based on our limited data and previous studies, we can counsel patients undergoing twin amniocentesis at mid-trimester that the fetal loss rate may be slightly higher than that of singleton amniocentesis. © 2008 Springer-Verlag.