Thyroid dysfunction in a patient with aglossia

We report a Thai girl who had aglossia, micrognathia, microsomia, collapse of mandibular arch, persistence of buccopharyngeal membrane, microcephaly, and mild developmental delay. Thyroid function tests indicated that she had subclinical hypothyroidism. Thyroid scan revealed normal uptake of the who...

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Main Authors: Kantaputra P., Tanpaiboon P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-0141523161&partnerID=40&md5=3437981fb03d99858b1289975f9928ac
http://www.ncbi.nlm.nih.gov/pubmed/12966532
http://cmuir.cmu.ac.th/handle/6653943832/2830
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-28302014-08-30T02:25:26Z Thyroid dysfunction in a patient with aglossia Kantaputra P. Tanpaiboon P. We report a Thai girl who had aglossia, micrognathia, microsomia, collapse of mandibular arch, persistence of buccopharyngeal membrane, microcephaly, and mild developmental delay. Thyroid function tests indicated that she had subclinical hypothyroidism. Thyroid scan revealed normal uptake of the whole thyroid gland. Tongue morphogenesis is integrally linked to the normal development of thyroid gland, and abnormal tongue morphogenesis could potentially result in a functional thyroid disorder. We propose that micrognathia, microsomia, congenital absence of mandibular incisors, and collapse of the mandibular arch are the result of abnormal tongue development. © 2003 Wiley-Liss, Inc. 2014-08-30T02:25:26Z 2014-08-30T02:25:26Z 2003 Article 15524825 12966532 AJMGD http://www.scopus.com/inward/record.url?eid=2-s2.0-0141523161&partnerID=40&md5=3437981fb03d99858b1289975f9928ac http://www.ncbi.nlm.nih.gov/pubmed/12966532 http://cmuir.cmu.ac.th/handle/6653943832/2830 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description We report a Thai girl who had aglossia, micrognathia, microsomia, collapse of mandibular arch, persistence of buccopharyngeal membrane, microcephaly, and mild developmental delay. Thyroid function tests indicated that she had subclinical hypothyroidism. Thyroid scan revealed normal uptake of the whole thyroid gland. Tongue morphogenesis is integrally linked to the normal development of thyroid gland, and abnormal tongue morphogenesis could potentially result in a functional thyroid disorder. We propose that micrognathia, microsomia, congenital absence of mandibular incisors, and collapse of the mandibular arch are the result of abnormal tongue development. © 2003 Wiley-Liss, Inc.
format Article
author Kantaputra P.
Tanpaiboon P.
spellingShingle Kantaputra P.
Tanpaiboon P.
Thyroid dysfunction in a patient with aglossia
author_facet Kantaputra P.
Tanpaiboon P.
author_sort Kantaputra P.
title Thyroid dysfunction in a patient with aglossia
title_short Thyroid dysfunction in a patient with aglossia
title_full Thyroid dysfunction in a patient with aglossia
title_fullStr Thyroid dysfunction in a patient with aglossia
title_full_unstemmed Thyroid dysfunction in a patient with aglossia
title_sort thyroid dysfunction in a patient with aglossia
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-0141523161&partnerID=40&md5=3437981fb03d99858b1289975f9928ac
http://www.ncbi.nlm.nih.gov/pubmed/12966532
http://cmuir.cmu.ac.th/handle/6653943832/2830
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