Development of Haplorchis taichui (Trematoda: Heterophyidae) in Mus musculus mice

The development of Haplorchis taichui was studied in sixteen mice, Mus musculus. Metacercarial cysts of H. taichui were obtained from the freshwater fish, Thynnichthys thynnoides, collected in Chiang Mai Province, north Thailand. Approximately 200 active metacercariae were orally introduced into eac...

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Bibliographic Details
Main Authors: Sukontason K., Sukontason K.L., Boonsriwong N., Chaithong U., Piangjai S., Choochote W.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-0035552193&partnerID=40&md5=444d29d52c3afded32e4471538d916d2
http://www.ncbi.nlm.nih.gov/pubmed/12041603
http://cmuir.cmu.ac.th/handle/6653943832/2836
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Institution: Chiang Mai University
Language: English
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Summary:The development of Haplorchis taichui was studied in sixteen mice, Mus musculus. Metacercarial cysts of H. taichui were obtained from the freshwater fish, Thynnichthys thynnoides, collected in Chiang Mai Province, north Thailand. Approximately 200 active metacercariae were orally introduced into each mouse. Two mice were randomly sacrificed and necropsied daily from day 2-9 postinfection (pi). Two peaks of increment in the length and width of worms were found at day 3 and 7 pi. H. taichui was rapid in maturation, similar to other minute intestinal flukes. Rudimentary sex organs were found at day 2 pi. Spermatozoa in a seminal receptacle, vitellaria and eggs were seen as early as 3 days pi. The number of eggs increased daily to ≈50-60 eggs thereafter. Mice can serve as a suitable experimental definitive host for harvesting adult H. taichui, especially in 1-week pi.