Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitope by CD8+ T cells and NK cells

Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitope by CD8+ T cells and NK cells

Objectives: The HIV-1 Nef protein selectively downregulates human leukocyte antigen (HLA)-A and HLA-B but not HLA-C molecules on the surface of infected cells. This allows HIV-infected cells to evade recognition by most cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. We investigated th...

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Bibliographic Details
Main Authors: Thananchai H., Makadzange T., Maenaka K., Kuroki K., Peng Y., Conlon C., Rowland-Jones S., Dong T.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-58849087061&partnerID=40&md5=099287798c25e5578852dde3053eea01
http://www.ncbi.nlm.nih.gov/pubmed/19098488
http://cmuir.cmu.ac.th/handle/6653943832/2916
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Institution: Chiang Mai University
Language: English

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http://www.scopus.com/inward/record.url?eid=2-s2.0-58849087061&partnerID=40&md5=099287798c25e5578852dde3053eea01
http://www.ncbi.nlm.nih.gov/pubmed/19098488
http://cmuir.cmu.ac.th/handle/6653943832/2916

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